What cases i use statistics to enhance performance large table?

I work on sql server 2012 i read more about statistics is very good for enahnce performance query

when or which cases i can use in it

can you show please

i don't need links or articles

i need only cases i use statistics and if i show execution plan

what indicator on execution plan that say

there is no statistics or remaining statistics

please help me

i read more about statistics and enhance large tables

so when i use it and which case or indicator execution plan that tell me must use statistics to enhance performance

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